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This is version 1.20 of the Surface Entropy Reduction prediction (SERp) server from January 2007. This exploratory tool aims to aid identification of sites that are most suitable for mutation designed to enhance crystallizability by a Surface Entropy Reduction approach.

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BLOCKS:
Blocks are multiply-aligned, ungapped segments corresponding to the most highly conserved regions of proteins. The search found the following 2 potential hit(s).

Block ID Annotation Blocks e Value 
[+] IPB000443: Islet amyloid protein (amylin) signature 3 of 4 4.75·10-12
[+] IPB002163: Beta-type calcitonin signature 2 of 2 7.04·10-3


PDB Homologs / DSSP:
The following 2 PDB structures of homologs were found with PSI-BLAST and are shown for your reference. The results from the DSSP analysis for solvent accessibility is provided upon expansion by clicking the [+] link.

PDB ID BLAST Ref Identity Annotation
[+] 3G7V: 241913343 100% B Chain B, Islet Amyloid Polypeptide (Iapp Or Amylin) Fused To Maltose...
[+] 3G7V: 241913343 100% B Chain B, Islet Amyloid Polypeptide (Iapp Or Amylin) Fused To Maltose...