This summary shows 3 cluster candidate(s) that contain residues suitable for mutation designed to confer enhanced crystallizability.
Select one cluster from this list and introduce all proposed mutations into the target. Typically only one cluster is used per construct.
Cluster candidates are presented in order of predicted success (best candidates with higher scores are shown first). Ideal mutation candidates are non-conserved, high entropy residues that
lie in surface-exposed, entropy-rich regions of the protein.
Good candidates for mutation typically have clusters scores of 3.0 and above.
See respective tabs (above) for scoring details, a graphical representation of the location in the sequence,
BLAST alignments to your sequence and complete results of the Meta Search.